- Hardcover: 384 pages
- Publisher: Wiley-Blackwell; 1 edition (26 June 2015)
- Language: English
- ISBN-10: 1118663438
- ISBN-13: 978-1118663431
- Product Dimensions: 18.5 x 2.3 x 26.2 cm
- Boxed-product Weight: 798 g
- Customer Reviews: 25 customer ratings
- Amazon Bestsellers Rank: 316,700 in Books (See Top 100 in Books)
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Vaccines and Autoimmunity Hardcover – 26 June 2015
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From the Back Cover
VACCINES & AUTOIMMUNITY
Edited by Yehuda Shoenfeld, Nancy Agmon-Levin and Lucija Tomljenovic
In light of the discovery of autoimmune/inflammatory syndrome induced by adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants - specifically aluminum - in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.
Vaccines and Autoimmunity is divided into three sections. The first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant-induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick building syndrome (SBS), safe vaccines, toll-like receptors (TLRs), TLRs in vaccines, pesticides as adjuvants, oil as an adjuvant, mercury, aluminum and autoimmunity. The second section reviews the literature on vaccines that have induced autoimmune conditions, such as MMR and HBV. The final section covers diseases in which vaccines are known to be the solicitor - for instance, systemic lupus erythematosus - and whether they can be induced by vaccines for MMR, HBV, HCV, and others.
Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.
Summary of how adjuvants can induce diverse autoimmune clinical manifestations in genetically prone subjects
- Review of the literature on all vaccines that have been found to induce autoimmune conditions
- Full discussion of autoimmune diseases in which vaccines are known to be the solicitor
- Excellent source for future pathogenic and epidemiological studies
- Edited and authored by leaders in the field
About the Author
Yehuda Shoenfeld is the Incumbent of the Laura Schwarz-Kipp Chair of Research of Autoimmune Diseases, Sackler Faculty of Medicine, Tel Aviv University in Tel Aviv, Israel. He is also Founder of the Center for Autoimmune Diseases, both at the Sheba Medical Center in Tel Hashomer, Israel.
Nancy Agmon-Levin is a specialist in Clinical Immunology and Allergology, and serves as Deputy Head of the Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center in Tel Hashomer, Israel. She is also President of the Israel Association for Allergy and Clinical Immunology (IAACI).
Lucija Tomljenovic is a Senior Postdoctoral Fellow in the Neural Dynamics Research Group at the University of British Columbia in Vancouver, BC, Canada.
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Review this product
Top international reviews
Editor: Shoenfeld, Yahuda with 77 Co-contributors
Wiley Press. 2015.
Key Points Excerpted By Kathryn C. Anderson
Updated: March 31, 2019
Vaccines have adverse reactions, including autoimmune disease.
Vaccine immune stimulators (adjuvants) “have been found to inflict illnesses of autoimmune nature, termed ‘the adjuvant diseases’”. (p. 17)
Patients are not screened for genetics that commonly predict adverse vaccination events (p. 3) Previous adverse reaction and family history of autoimmune disease are susceptibility factors. (p. 3) Epidemiological studies can not detect these patients. (p. 61)
Mounting evidence that adjuvants may cause: (p. 35)
Aluminum used in many vaccines to stimulate an immune reaction:
Can remain in the body up to 11 years (p. 48)
Can reach a threshold level in the body after multiple vaccinations: Aluminum becomes an antigen. (p. 50) As many as 1% may be sensitized to future Al exposure.
Food sensitivity is the most common non-neurological response. (p. 50) Symptoms: intestinal inflammation and diarrhea.
Can lodge in CNS where it can drive further deleterious immunoinflammatory processes, resulting in brain inflammation and long term neural dysfunction (p. 48)
Can trigger pathological immune responses (p. 48)
Hep B (with Aluminum) vaccine given on the first day of life in the United States can trigger 6 neurological diseases, including multiple sclerosis (p. 49)
Induces changes to membrane phospholipids (cell membranes) making the nerve tissue myelin sheath a common target (p. 49)
Aluminum has poor effect on innate immune response needed for pathogens (p. 20)
Animal models with autoimmune susceptibility are “rapidly doomed to autoimmunity as they undergo adjuvant administration”. ( p. 39)
“Further studies are warranted… to definitely state the caution required for autoimmunity-bearing patients.” ( p. 39)
Adverse vaccine reactions, “chronic fatigue, myalgias, and cognitive impairment”, must be considered by researchers and clinicians. (p. 51)
The common faulty vaccine test method of using Aluminum in the placebo group can “no longer be justified”. (p. 51)
I have had the book a couple of weeks now and have purused it. The chapters summarize the existing medical research on the topic of vaccines and autoimmunity. At first, I was concerned there was too much corporate influenced science reflected in the summaries in the book, but after further scrutiny I believe this book is a very credible work, and a landmark one. In at least one case, the editors do mention that a study concluding the vaccine in question did not cause the disease in question was sponsored by the vaccine manufacturer and was therefore probably biased. This information markedly increases my confidence in the summaries provided. In addition, they do not beat around the bush when discussing the subject of aluminum adjuvants and the neurological, genetic, and immune system harm they are known to do. This frank discussion by leading researchers in the field of vaccines and autoimmunity directly contradicts the headlines that regularly scream across magazines, newspapers and web pages, and points the finger at nanonized aluminum adjuvants as a factor in many modern epidemics, including Alzheimer's, Parkinson's, and Autism. The book is an extremely valuable reference to locate the most important studies in any given area.