Serbia is one of the countries with statistical evidence of inadequate morphine consumption per capita. In 2006, the adequacy of opioid analgesic consumption was only 8% - based on a per capita consumption of 12.81 morphine equivalents (mEq) while 166mEq would have been adequate for treatment of all pain conditions (Data for Serbia and Montenegro). Serbia was selected as one of the countries to participate in the ATOME project due to its low per capita morphine consumption. Four years later, in 2010, the adequacy of opioid analgesic consumption had slightly increased (both in absolute and in relative terms) – it was 14% (based on a per capita consumption of opioid analgesics of 40.06morphine equivalents (mEq) while 285.61mEq in mg per capita would have been adequate). This report presents a summary of the results of the situational analysis that has been undertaken with regard to opioid availability and accessibility in Serbia. The results of the situational analysis are divided in two parts: the first part addresses legal and regulatory issues and the second part focuses on issues relating to policy. Both parts present the main barriers and recommendations for improving access to opioid medication in Serbia.