England. 1535. Jane Seymour is 27 years old and increasingly desperate for the marriage that will provide her a real place in the world. She gets the perfect opportunity to shine when the court visits Wolf Hall, the Seymour ancestral manor. With new poise born from this event, it seems certain that her efficiency and diligence will shine through and finally attract a suitor.
Meanwhile, King Henry VIII is 45 and increasingly desperate for a son to secure his legacy. He left his first wife, a princess of Spain, changing his country's religion in the process, to marry Anne Boleyn -- but she too has failed to deliver the promised heir. As Henry begins to fear he is cursed, Jane Seymour's honesty and innocence conjure redemption. Thomas Cromwell, an ambitious clerk who has built a career on strategically satisfying the King's desires, sees in Jane the perfect vehicle to calm the political unrest that threatens the country: he engineers the plot that ends with Jane becoming the King's third wife.
Jane believes herself virtuous and her actions justified, but early miscarriages shake her confidence and hopes. How can a woman who has done nothing wrong herself deal with the guilt of how she unseated her predecessor?