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T. A. Brown

Genomes 4 Paperback – 24 May 2017

by T. Brown (Author)

34 ratings

Edition: 4^th

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Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.

Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.

Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.

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Product details

ASIN : 0815345089

Publisher : Garland Science; 4th edition (24 May 2017)

Language : English

Paperback : 524 pages

ISBN-10 : 9780815345084

ISBN-13 : 978-0815345084

Dimensions : 21.34 x 2.29 x 27.43 cm

Best Sellers Rank: 244,249 in Books (See Top 100 in Books)

127 in Molecular Biology (Books)

285 in Biochemistry (Books)

533 in Genetics (Books)

Customer Reviews:
34 ratings

Product description

About the Author

Terry Brown is professor of Biomolecular Archaeology at Manchester University. As well as writing the previous editions of Genomes, he is the author of Introduction to Genetics: A Molecular Approach (Garland 2011) and 5 editions of DNA Cloning & Analysis (Wiley Blackwell). He is also an experienced teacher of genetics.

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4.6 out of 5
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Skarrah
Recommended
Reviewed in the United Kingdom on 22 March 2021
Verified Purchase
Great introductory text. Things are clearly explained. Use of diagrams etc is good. Includes questions at the end of the chapters to help you test your understanding of the topics.
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Lauren Barker
A must for medical genetics
Reviewed in the United Kingdom on 21 October 2018
Verified Purchase
A must for medical genetics
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LUIGI C MINCHELLA
Comprehensive
Reviewed in the United Kingdom on 6 April 2021
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Revision well laid out
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IM
Libro clásico
Reviewed in Spain on 16 September 2019
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Tengo desde la primera edición. Buena introducción al tema, pero no apropiada para expertos, que la encontrarán un poco simple. Principalmente por tanto para estudiantes.
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Aditya Kumar
Extremely important to read latest version of books
Reviewed in India on 21 March 2019
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Up-to-date content
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